In this paper proposed a statistical model of the optoacoustic transformation in the moving liquid medium using nanoparticles for a noninvasive blood analysis system. Since to increase the accuracy of measurements should take into account the probabilistic nature of the distribution of nanoscale objects as contrast agents in the blood stream in the human cardiovascular system. To determine the statistical characteristics of the component of the sound signal formed by a conglomerate of nanoscale objects using Monte Carlo simulation. Main static characteristics were calculated and the density distribution of the probability of the normalized amplitude of the sound signal was determined for a series of numerical experiments.
Keywords: optoacoustics, optoacoustic effect, flow cytometry, acoustic signal, carbon nanotubes, laser sound excitation, statistical analysis
Regarding the structural evaluation of the instrumental error of bio MIS tool software package was developed that allows to take into account the error in the analysis of clinical diagnostic measurement in hematology research. It allows to analyze the results of hematological measurements with the measurement error and issue you with a message that characterizes getting results within normal or unreliability. Nanoparticles in biomedical analytical measurements are used as contrast agents, since, being immobilized specific proteins with adhesion to the diseased cells and bacteria. Register ultrasonic signal produced when the laser blood flow to the entered nanoparticles allows the detection and enumeration of diseased cells. The block diagram of analytical studies was designed to prove its basic metrological characteristics. Research is conducted in the centers for collective use of the Southern Federal University "Nanotechnology" and "Laser Technology", equipped with modern and unique nanotechnology research equipment.
Keywords: Bio MIS, nanoparticles, hematological measurements